BDBM333146 Compound I::US10196404, Example 1::US10196404, Example 2::US10196404, Example 3::US11472816, Example 3::US11691989, Compound AZD5991

SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCc5c(C(O)=O)n(C)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)nn1C

InChI Key InChIKey=KBQCEQAXHPIRTF-UHFFFAOYSA-N

Data  4 KI  15 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 333146   

LigandPNGBDBM333146(Compound I | US10196404, Example 1 | US10196404, E...)
Affinity DataIC50: <3nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair
LigandPNGBDBM333146(Compound I | US10196404, Example 1 | US10196404, E...)
Affinity DataIC50: <3nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair
LigandPNGBDBM333146(Compound I | US10196404, Example 1 | US10196404, E...)
Affinity DataIC50:  67nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair