BDBM333146 Compound I::US10196404, Example 1::US10196404, Example 2::US10196404, Example 3::US11472816, Example 3::US11691989, Compound AZD5991
SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCc5c(C(O)=O)n(C)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)nn1C
InChI Key InChIKey=KBQCEQAXHPIRTF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333146
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Human)
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <3nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Human)
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <3nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Human)
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: 67nMAssay Description:The assay was constructed such that GST tagged Mcl-1 protein, was incubated with a Europium-labeled anti-GST antibody and a HyLite Fluor 647-labeled ...More data for this Ligand-Target Pair